Detection of disseminated tumor cells in the bone marrow of breast cancer patients using multiplex gene expression measurements identifies new therapeutic targets in patients at high risk for the development of metastatic disease

PURPOSE: Disseminated tumor cells (DTCs) detected in the bone marrow of breast cancer patients identifies women at high risk of recurrence. DTCs are traditionally detected by immunocytochemical staining for cytokeratins or single gene expression measurements, which limit both specificity and sensiti...

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Publicado en:Breast Cancer Res Treat
Main Authors: Siddappa, Chidananda M., Watson, Mark A., Pillai, Sreeraj, Trinkaus, Kathryn, Fleming, Timothy, Aft, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920139/
https://ncbi.nlm.nih.gov/pubmed/23129172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2279-y
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