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A simple method to control over-alignment in the MAFFT multiple sequence alignment program

Motivation: We present a new feature of the MAFFT multiple alignment program for suppressing over-alignment (aligning unrelated segments). Conventional MAFFT is highly sensitive in aligning conserved regions in remote homologs, but the risk of over-alignment is recently becoming greater, as low-qual...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Katoh, Kazutaka, Standley, Daron M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920119/
https://ncbi.nlm.nih.gov/pubmed/27153688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw108
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