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Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation?

Despite major advances in recent years, graft-versus-host disease (GVHD) remains a major life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT). To improve our therapeutic armory against GVHD, preclinical evidence is most frequently generated in mouse and large ani...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Zeiser, Robert, Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920018/
https://ncbi.nlm.nih.gov/pubmed/26994149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-699082
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