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The somatotropic axis in human aging: Framework for the current state of knowledge and future research

Mutations resulting in reduced signaling of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis are associated with increased life and health-span across model organisms. Similar findings have been noted in human cohorts with functional mutations in the somatotropic axis, suggesting that...

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Библиографические подробности
Опубликовано в: :Cell Metab
Главные авторы: Milman, Sofiya, Huffman, Derek M., Barzilai, Nir
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919980/
https://ncbi.nlm.nih.gov/pubmed/27304500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.05.014
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