Vascular-targeted TNFα and IFNγ inhibits orthotopic colorectal tumor growth

BACKGROUND: Tumor necrosis factor alpha (TNFα) and interferon gamma (IFNγ) were originally identified to show potent anti-tumor activity and immunomodulatory capability. Unfortunately, several clinical studies of relevant cancer therapy did not observe significant response in maximum tolerated dose...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Shen, Jing, Li, Zhi Jie, Li, Long Fei, Lu, Lan, Xiao, Zhan Gang, Wu, William Ka Kei, Zhang, Lin, Li, Ming Xing, Hu, Wei, Chan, Kam Ming, Cho, Chi Hin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919862/
https://ncbi.nlm.nih.gov/pubmed/27342639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0944-3
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