The anti-angiogenic effect and novel mechanisms of action of Combretastatin A-4

Combretastatin A-4 (CA4) is the lead compound of a relatively new class of vascular disrupting agents that target existing tumor blood vessels. Recent studies showed the CA4 might inhibit angiogenesis. However, the underlying molecular mechanisms by which CA4 exerts its anti-angiogenic effects are n...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Su, Min, Huang, Jingjia, Liu, Suyou, Xiao, Yuhang, Qin, Xiyuan, Liu, Jia, Pi, Chaoqiong, Luo, Tiao, Li, Jijia, Chen, Xianghui, Luo, Zhiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919637/
https://ncbi.nlm.nih.gov/pubmed/27338725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28139
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