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Sliding and intermolecular transfer of the lac repressor: kinetic perturbation of a reaction intermediate by a distant DNA sequence.

The lac repressor associates with its operator at a rate faster than conventional diffusion allows, either because of one-dimensional diffusion of a captured repressor along the DNA (sliding) or because the tetrameric repressor can be rapidly transferred between DNA sites distant from each other in...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ruusala, T, Crothers, D M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4903
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