Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

Full-length (FL) docking protein-1 (DOK1) is an adapter protein which inhibits growth factor and immune response pathways in normal tissues, but is frequently lost in human cancers. Small DOK1 variants remain in cells of solid tumors and leukemias, albeit, their functions are elusive. To assess the...

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發表在:EBioMedicine
Main Authors: Friedrich, Teresa, Söhn, Michaela, Gutting, Tobias, Janssen, Klaus-Peter, Behrens, Hans-Michael, Röcken, Christoph, Ebert, Matthias P.A., Burgermeister, Elke
格式: Artigo
語言:Inglês
出版: Elsevier 2016
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919572/
https://ncbi.nlm.nih.gov/pubmed/27428427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.05.003
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