Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

Full-length (FL) docking protein-1 (DOK1) is an adapter protein which inhibits growth factor and immune response pathways in normal tissues, but is frequently lost in human cancers. Small DOK1 variants remain in cells of solid tumors and leukemias, albeit, their functions are elusive. To assess the...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Friedrich, Teresa, Söhn, Michaela, Gutting, Tobias, Janssen, Klaus-Peter, Behrens, Hans-Michael, Röcken, Christoph, Ebert, Matthias P.A., Burgermeister, Elke
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919572/
https://ncbi.nlm.nih.gov/pubmed/27428427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.05.003
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