Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival

SCRIB is a polarity regulator known to be abnormally expressed in cancer at the protein level. Here we report that, in breast cancer, an additional and hidden dimension of deregulations exists: an unexpected SCRIB exon usage pattern appears to mark a more malignant tumor phenotype and significantly...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Metodieva, Gergana, Adoki, Samson, Lausen, Berthold, Metodiev, Metodi V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919504/
https://ncbi.nlm.nih.gov/pubmed/27428426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.05.009
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