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Tyrosine Residue in the TRPV1 Vanilloid Binding Pocket Regulates Deactivation Kinetics
Vanilloids are pain evoking molecules that serve as ligands of the “heat and capsaicin receptor” TRPV1. Binding of either endogenous or exogenous vanilloids evokes channel and subsequent neuronal activation, leading to pain sensation. Despite its pivotal physiological role, the molecular basis of TR...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919467/ https://ncbi.nlm.nih.gov/pubmed/27143360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726372 |
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