Secreted Frizzled-related Protein 2 (sFRP2) Redirects Non-canonical Wnt Signaling from Fz7 to Ror2 during Vertebrate Gastrulation

Convergent extension movements during vertebrate gastrulation require a balanced activity of non-canonical Wnt signaling pathways, but the factors regulating this interplay on the molecular level are poorly characterized. Here we show that sFRP2, a member of the secreted frizzled-related protein (sF...

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Publicat a:J Biol Chem
Autors principals: Brinkmann, Eva-Maria, Mattes, Benjamin, Kumar, Rahul, Hagemann, Anja I. H., Gradl, Dietmar, Scholpp, Steffen, Steinbeisser, Herbert, Kaufmann, Lilian T., Özbek, Suat
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919455/
https://ncbi.nlm.nih.gov/pubmed/27129770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733766
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