RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells

Inflammatory breast cancer (IBC) is an extremely lethal cancer that rapidly metastasizes. Although the molecular attributes of IBC have been described, little is known about the underlying metabolic features of the disease. Using a variety of metabolic assays, including (13)C tracer experiments, we...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wynn, Michelle L., Yates, Joel A., Evans, Charles R., Van Wassenhove, Lauren D., Wu, Zhi Fen, Bridges, Sydney, Bao, Liwei, Fournier, Chelsea, Ashrafzadeh, Sepideh, Merrins, Matthew J., Satin, Leslie S., Schnell, Santiago, Burant, Charles F., Merajver, Sofia D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919454/
https://ncbi.nlm.nih.gov/pubmed/27129239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703959
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