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The Globular Tail Domain of Myosin-5a Functions as a Dimer in Regulating the Motor Activity
Myosin-5a contains two heavy chains, which are dimerized via the coiled-coil regions. Thus, myosin-5a comprises two heads and two globular tail domains (GTDs). The GTD is the inhibitory domain that binds to the head and inhibits its motor function. Although the two-headed structure is essential for...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919443/ https://ncbi.nlm.nih.gov/pubmed/27129208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.724328 |
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