Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide

Diallyl trisulfide (DATS), a metabolic byproduct of garlic, is known to inhibit the growth of breast cancer cells in vitro and in vivo. This study demonstrates that DATS targets breast cancer stem cells (bCSC). Exposure of MCF-7 and SUM159 human breast cancer cells to pharmacological concentrations...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Kim, Su-Hyeong, Kaschula, Catherine H., Priedigkeit, Nolan, Lee, Adrian V., Singh, Shivendra V.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919436/
https://ncbi.nlm.nih.gov/pubmed/27129776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715219
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