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Membrane-Spanning Sequences in Endoplasmic Reticulum Proteins Promote Phospholipid Flip-Flop

The mechanism whereby phospholipids rapidly flip-flop in the endoplasmic reticulum (ER) membrane remains unknown. We previously demonstrated that the presence of a hydrophilic residue in the center of the model transmembrane peptide sequence effectively promoted phospholipid flip-flop and that hydro...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Nakao, Hiroyuki, Ikeda, Keisuke, Ishihama, Yasushi, Nakano, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919424/
https://ncbi.nlm.nih.gov/pubmed/27332127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.023
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