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Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo

The acidic extracellular environment of tumors potentiates their aggressiveness and metastasis, but few methods exist to selectively modulate the extracellular pH (pHe) environment of tumors. Transient flushing of biological systems with alkaline fluids or proton pump inhibitors is impractical and n...

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Détails bibliographiques
Publié dans:Nanoscale
Auteurs principaux: Som, Avik, Raliya, Ramesh, Tian, Limei, Akers, Walter, Ippolito, Joseph, Singamaneni, Srikanth, Biswas, Pratim, Achilefu, Samuel
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919221/
https://ncbi.nlm.nih.gov/pubmed/26745389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr06162h
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