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Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing

OBJECTIVE: Human macrophages can shift phenotype across the inflammatory M1 and reparative M2 spectrum in response to environmental challenges, but the mechanisms promoting inflammatory and cardiometabolic disease-associated M1 phenotypes remain incompletely understood. Alternative splicing (AS) is...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Lin, Jennie, Hu, Yu, Nunez, Sara, Foulkes, Andrea S., Cieply, Benjamin, Xue, Chenyi, Gerelus, Mark, Li, Wenjun, Zhang, Hanrui, Rader, Daniel J., Musunuru, Kiran, Li, Mingyao, Reilly, Muredach P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919157/
https://ncbi.nlm.nih.gov/pubmed/27230130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307573
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