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Anticipatory activation of the unfolded protein response by epidermal growth factor is required for immediate early gene expression and cell proliferation()

The onco-protein epidermal growth factor (EGF) initiates a cascade that includes activation of the ERK and AKT signaling pathways and alters gene expression. We describe a new action of EGF–EGF receptor (EGFR), rapid anticipatory activation of the endoplasmic reticulum stress sensor, the unfolded pr...

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Bibliografiske detaljer
Udgivet i:Mol Cell Endocrinol
Main Authors: Yu, Liqun, Andruska, Neal, Zheng, Xiaobin, Shapiro, David J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919024/
https://ncbi.nlm.nih.gov/pubmed/26551735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.11.005
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