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Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I.

Malignant glioma is the most common brain tumor. The molecular basis of glioma tumorigenicity has not been defined. Cultured glioma cells accumulate high levels of insulin-like growth factor I (IGF-I) transcripts. We asked whether IGF-I expression is coupled to tumorigenicity, using a combined in vi...

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Gespeichert in:
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Trojan, J, Blossey, B K, Johnson, T R, Rudin, S D, Tykocinski, M, Ilan, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
Schlagworte:
Research Article
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4874
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