An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs

Rabies is a zoonotic infectious disease of the central nervous system (CNS). In unvaccinated or untreated subjects, rabies virus infection causes severe neurological symptoms and is invariably fatal. Despite the long-standing existence of effective vaccines, vaccine availability remains insufficient...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Schnee, Margit, Vogel, Annette B., Voss, Daniel, Petsch, Benjamin, Baumhof, Patrick, Kramps, Thomas, Stitz, Lothar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918980/
https://ncbi.nlm.nih.gov/pubmed/27336830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004746
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