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Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors

Small molecule effectors regulate gene transcription in bacteria by altering the DNA-binding affinities of specific repressor proteins. Although the GntR proteins represent a large family of bacterial repressors, only little is known about the allosteric mechanism that enables their function. DasR f...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Fillenberg, Simon B., Friess, Mario D., Körner, Samuel, Böckmann, Rainer A., Muller, Yves A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918961/
https://ncbi.nlm.nih.gov/pubmed/27337024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157691
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