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Diagnostic Accuracy of PIK3CA Mutation Detection by Circulating Free DNA in Breast Cancer: A Meta-Analysis of Diagnostic Test Accuracy

Mutation of p110 alpha-catalytic subunit of phosphatidylinositol 3-kinase (PIK3CA) has high predictive and prognostic values for breast cancer. Hence, there has been a marked interest in detecting and monitoring PIK3CA genotype with non-invasive technique, such as circulating free DNA (cfDNA). Howev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Yidong, Wang, Changjun, Zhu, Hanjiang, Lin, Yan, Pan, Bo, Zhang, Xiaohui, Huang, Xin, Xu, Qianqian, Xu, Yali, Sun, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918940/
https://ncbi.nlm.nih.gov/pubmed/27336598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158143
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