Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes

Background. Tick transmission of Borrelia spirochetes to humans results in significant morbidity from Lyme disease worldwide. Serum concentrations of antibodies against outer surface protein A (OspA) were shown to correlate with protection from infection with Borrelia burgdorferi, the primary cause...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Wang, Yang, Kern, Aurélie, Boatright, Naomi K., Schiller, Zachary A., Sadowski, Andrew, Ejemel, Monir, Souders, Colby A., Reimann, Keith A., Hu, Linden, Thomas, William D., Klempner, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918831/
https://ncbi.nlm.nih.gov/pubmed/27338767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw151
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