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Haplotype analysis of BRCA1 intragenic markers in Iranian patients with familial breast and ovarian cancer

BACKGROUND: Breast cancer is the most common malignancy in women. Breast Cancer Type 1 Susceptibility gene (BRCA1) is a tumor suppressor gene, involved in DNA damage repair and in 81% of the breast-ovarian cancer families were due to BRCA1. In some clinically investigated genes, the intragenic marke...

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Detalhes bibliográficos
Publicado no:Int J Reprod Biomed
Main Authors: Miresmaeili, Seyed Mohsen, Kordi Tamandani, Dor Mohammad, Kalantar, Seyed Mehdi, Moshtaghioun, Seyed Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: Research and Clinical Center for Infertility 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918776/
https://ncbi.nlm.nih.gov/pubmed/27351029
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