Loading...
Li–Fraumeni Syndrome
Li–Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by a germline mutation of the TP53 gene on chromosome 17p13.1. It has an autosomal dominant pattern of inheritance with high penetrance. These patients have a very high lifetime cumulative risk of developing multiple malignancies...
Saved in:
| Published in: | J Pediatr Genet |
|---|---|
| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Georg Thieme Verlag KG
2016
|
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918696/ https://ncbi.nlm.nih.gov/pubmed/27617148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0036-1579759 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|