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Recessive optic atrophy, sensorimotor neuropathy and cataract associated with novel compound heterozygous mutations in OPA1

Mutations in the optic atrophy 1 gene (OPA1) are associated with autosomal dominant optic atrophy and 20% of patients demonstrate extra-ocular manifestations. In addition to these autosomal dominant cases, only a few syndromic cases have been reported thus far with compound heterozygous OPA1 mutatio...

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Publicat a:Mol Med Rep
Autors principals: LEE, JINHO, JUNG, SUNG-CHUL, HONG, YOUNG BIN, YOO, JEONG HYUN, KOO, HEASOO, LEE, JA HYUN, HONG, HYUN DAE, KIM, SANG-BEOM, CHUNG, KI WHA, CHOI, BYUNG-OK
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918608/
https://ncbi.nlm.nih.gov/pubmed/27150940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5209
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