Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

Tumor necrosis factor alpha (TNF alpha), a primary mediator of systemic responses to sepsis and infection, can be injurious to the organism when present in excessive quantities. Here we report that two types of naturally occurring soluble TNF receptors (sTNFR-I and sTNFR-II) circulate in human exper...

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Autori principali: Van Zee, K J, Kohno, T, Fischer, E, Rock, C S, Moldawer, L L, Lowry, S F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC49184/
https://ncbi.nlm.nih.gov/pubmed/1317575
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