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Gene Silencing of CENP-E by Small Interfering RNA in HeLa Cells Leads to Missegregation of Chromosomes after a Mitotic Delay

Centromeric protein-E (CENP-E) is a kinesin-like motor protein required for chromosome congression at prometaphase. Functional perturbation of CENP-E by various methods results in a consistent phenotype, i.e., unaligned chromosomes during mitosis. One unresolved question from previous studies is whe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tanudji, Marcel, Shoemaker, John, L'Italien, Lawrence, Russell, Loren, Chin, Gregory, Schebye, Xiao Min
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC491836/
https://ncbi.nlm.nih.gov/pubmed/15181147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0482
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