Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis

Microtubule nucleation is highly regulated during the eukaryotic cell cycle, but the underlying molecular mechanisms are largely unknown. During mitosis in fission yeast Schizosaccharomyces pombe, cytoplasmic microtubule nucleation ceases simultaneously with intranuclear mitotic spindle assembly. Cy...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Borek, Weronika E., Groocock, Lynda M., Samejima, Itaru, Zou, Juan, de Lima Alves, Flavia, Rappsilber, Juri, Sawin, Kenneth E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918325/
https://ncbi.nlm.nih.gov/pubmed/26243668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8929
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