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The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores

Accumulation of PLK1 at kinetochores is essential for chromosome alignment and segregation; however, the mechanism underlying PLK1 recruitment to kinetochores remains unresolved. The chromatin remodeller RSF1 tightly associates with centromere proteins, but its mitotic function is unknown. Here we s...

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Pubblicato in:Nat Commun
Autori principali: Lee, Ho-Soo, Park, Yong-Yea, Cho, Mi-Young, Chae, Sunyoung, Yoo, Young-Suk, Kwon, Myung-Hee, Lee, Chang-Woo, Cho, Hyeseong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918322/
https://ncbi.nlm.nih.gov/pubmed/26259146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8904
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