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Cholera Toxin Toxicity Does Not Require Functional Arf6- and Dynamin-dependent Endocytic Pathways

Cholera toxin (CT) and related AB(5) toxins bind to glycolipids at the plasma membrane and are then transported in a retrograde manner, first to the Golgi and then to the endoplasmic reticulum (ER). In the ER, the catalytic subunit of CT is translocated into the cytosol, resulting in toxicity. Using...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Massol, Ramiro H., Larsen, Jakob E., Fujinaga, Yukako, Lencer, Wayne I., Kirchhausen, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC491824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15146065/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-04-0283
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