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Chlorella virus pyrimidine dimer glycosylase and Escherichia coli endonucleases IV and V have incision activity on 2,2,4-triamino-5(2H)-oxazolone

INTRODUCTION: 2,2,4-Triamino-5(2H)-oxazolone (Oz) in a DNA strand is an oxidation product of guanine and 8-oxo-7, 8-dihydroguanine, and such a lesion can cause G-to-C transversions. Previously, Fpg/Nei and Nth were shown to have incision activity on Oz. FINDINGS: We investigated the activities of ch...

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Bibliografische gegevens
Gepubliceerd in:Genes Environ
Hoofdauteurs: Kino, Katsuhito, Suzuki, Masayo, Morikawa, Masayuki, Kobayashi, Takanobu, Iwai, Shigenori, Miyazawa, Hiroshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918129/
https://ncbi.nlm.nih.gov/pubmed/27350817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0022-8
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