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MUFFINN: cancer gene discovery via network analysis of somatic mutation data
A major challenge for distinguishing cancer-causing driver mutations from inconsequential passenger mutations is the long-tail of infrequently mutated genes in cancer genomes. Here, we present and evaluate a method for prioritizing cancer genes accounting not only for mutations in individual genes b...
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| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918128/ https://ncbi.nlm.nih.gov/pubmed/27333808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0989-x |
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