PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newborns

BACKGROUND: Children exposed to gestational diabetes mellitus (GDM) are at a higher risk of developing obesity and type 2 diabetes. This susceptibility might involve brown adipose tissue (BAT), which is suspected to protect against obesity. The objective of this study is to assess whether fetal expo...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Côté, Sandra, Gagné-Ouellet, Valérie, Guay, Simon-Pierre, Allard, Catherine, Houde, Andrée-Anne, Perron, Patrice, Baillargeon, Jean-Patrice, Gaudet, Daniel, Guérin, Renée, Brisson, Diane, Hivert, Marie-France, Bouchard, Luigi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918074/
https://ncbi.nlm.nih.gov/pubmed/27340502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0239-9
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