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Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents

BACKGROUND: Transgenic gpt delta mouse and rat models were developed to perform gpt and Spi(−) assays for in vivo mutagenicity tests. The animals were established by integration of lambda EG10 phage DNA as a transgene into the genome. The inserted position of the transgene on chromosome was determin...

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Detalhes bibliográficos
Publicado no:Genes Environ
Main Authors: Masumura, Kenichi, Sakamoto, Yasuteru, Kumita, Wakako, Honma, Masamitsu, Nishikawa, Akiyoshi, Nohmi, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918054/
https://ncbi.nlm.nih.gov/pubmed/27350819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-015-0024-6
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