Genetic and environmental risk factors for atherosclerosis regulate transcription of phosphatase and actin regulating gene PHACTR1

BACKGROUND AND AIMS: Coronary artery disease (CAD) risk is associated with non-coding genetic variants at the phosphatase and actin regulating protein 1(PHACTR1) gene locus. The PHACTR1 gene encodes an actin-binding protein with phosphatase regulating activity. The mechanism whereby PHACTR1 influenc...

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Publicado no:Atherosclerosis
Main Authors: Reschen, Michael E., Lin, Da, Chalisey, Anil, Soilleux, Elizabeth J., O’Callaghan, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917897/
https://ncbi.nlm.nih.gov/pubmed/27187934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2016.04.025
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