טוען...
Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
MOB1 protein is a key regulator of large tumor suppressor 1/2 (LATS1/2) kinases in the Hippo pathway. MOB1 is present in an autoinhibited form and is activated by MST1/2-mediated phosphorylation, although the precise mechanisms responsible for autoinhibition and activation are unknown due to lack of...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917820/ https://ncbi.nlm.nih.gov/pubmed/27335147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28488 |
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