Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction

Mitochondria alter their shape by undergoing cycles of fusion and fission. Changes in mitochondrial morphology impact on the cellular response to stress, and their interactions with other organelles such as the sarcoplasmic reticulum (SR). Inhibiting mitochondrial fission can protect the heart again...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hall, A R, Burke, N, Dongworth, R K, Kalkhoran, S B, Dyson, A, Vicencio, J M, Dorn II, G W, Yellon, D M, Hausenloy, D J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917668/
https://ncbi.nlm.nih.gov/pubmed/27228353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.139
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