Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice

Acetaminophen (N-acetyl-para-aminophenol (APAP)) toxicity causes acute liver failure by inducing centrilobular hepatic damage as a consequence of mitochondrial oxidative stress. Sterile inflammation, triggered by hepatic damage, facilitates gut bacterial translocation leading to systemic inflammatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Barman, P K, Mukherjee, R, Prusty, B K, Suklabaidya, S, Senapati, S, Ravindran, B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917664/
https://ncbi.nlm.nih.gov/pubmed/27171266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.131
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