Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses

Clusterin (Clu), an extracellular chaperone, exhibits characteristics of soluble innate immunity receptors, as assessed by its ability to bind some bacteria strains. In this study, we report that Clu also binds specifically to late apoptotic cells but not to live, early apoptotic, or necrotic cells....

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Cunin, P, Beauvillain, C, Miot, C, Augusto, J-F, Preisser, L, Blanchard, S, Pignon, P, Scotet, M, Garo, E, Fremaux, I, Chevailler, A, Subra, J-F, Blanco, P, Wilson, M R, Jeannin, P, Delneste, Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917652/
https://ncbi.nlm.nih.gov/pubmed/27148688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.113
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