Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis

Mitochondrial impairment induced by oxidative stress is a main characteristic of intrinsic cell death pathways in neurons underlying the pathology of neurodegenerative diseases. Therefore, protection of mitochondrial integrity and function is emerging as a promising strategy to prevent neuronal dama...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Neitemeier, S, Dolga, A M, Honrath, B, Karuppagounder, S S, Alim, I, Ratan, R R, Culmsee, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917646/
https://ncbi.nlm.nih.gov/pubmed/27148687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.107
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