How frequently are predicted peptides actually recognized by CD8 cells?

Detection of antigen-specific CD8 cells frequently relies on the use of peptides that are predicted to bind to HLA Class I molecules or have been shown to induce immune responses. There is extensive knowledge on individual HLA alleles’ peptide-binding requirements, and immunogenic peptides for many...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Moldovan, Ioana, Targoni, Oleg, Zhang, Wenji, Sundararaman, Srividya, Lehmann, Paul V.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
Fag:
Focussed Research Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917593/
https://ncbi.nlm.nih.gov/pubmed/27108305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1840-7
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