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Genetic and pharmacological manipulation of Glyoxalase 1 regulates voluntary ethanol consumption in mice

Previous studies have identified an association between the gene glyoxalase 1 (Glo1) and anxiety-like behavior in mice and have shown that the substrate of GLO1, methylglyoxal, is a competitive partial agonist at GABA(A) receptors. Given the well-established role of GABA(A) receptors in the behavior...

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Publicat a:Addict Biol
Autors principals: McMurray, Katherine M. J., Sidhu, Preetpal S., Cook, James M., Arnold, Leggy A., Palmer, Abraham A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917470/
https://ncbi.nlm.nih.gov/pubmed/26691867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12333
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