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A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine

Drug candidates exhibiting well-defined pharmacokinetic and pharmacodynamic profiles that are otherwise safe often fail to demonstrate proof-of-concept in phase II and III trials. Innovation in drug discovery and development has been identified as a critical need for improving the efficiency of drug...

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Detalles Bibliográficos
Publicado en:J Biomol Screen
Autores principales: Stern, Andrew M., Schurdak, Mark E., Bahar, Ivet, Berg, Jeremy M., Taylor, D. Lansing
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917453/
https://ncbi.nlm.nih.gov/pubmed/26962875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116635818
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