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Propofol Mitigates Learning and Memory Impairment After Electroconvulsive Shock in Depressed Rats by Inhibiting Autophagy in the Hippocampus

BACKGROUND: The present study explored the effects of propofol on hippocampal autophagy and synaptophysin in depression-model rats undergoing electroconvulsive shock (ECS). MATERIAL/METHODS: The rat depression model was established by exposing Sprague-Dawley rats to stress for 28 consecutive days. F...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Li, Ping, Hao, Xue-chao, Luo, Jie, Lv, Feng, Wei, Ke, Min, Su
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917309/
https://ncbi.nlm.nih.gov/pubmed/27203836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897765
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