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Mutation in HFE gene decreases manganese accumulation and oxidative stress in the brain after olfactory manganese exposure

Increased accumulation of manganese (Mn) in the brain is significantly associated with neurobehavioral deficits and impaired brain function. Airborne Mn has a high systemic bioavailability, and can be directly taken up into the brain, making it highly neurotoxic. While Mn transport is in part mediat...

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Detalhes bibliográficos
Publicado no:Metallomics
Main Authors: Ye, Qi, Kim, Jonghan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917014/
https://ncbi.nlm.nih.gov/pubmed/27295312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00080k
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