Relevance of the immunoglobulin V(H) somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens

Although immunoglobulin V(H) mutation status (IgV(H) MS) is prognostic in patients with chronic lymphocytic leukemia (CLL) who are treated with alkylating agents or single-agent fludarabine, its significance in the era of chemoimmunotherapy is not known. We determined the IgV(H) somatic mutation sta...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Lin, Katherine I., Tam, Constantine S., Keating, Michael J., Wierda, William G., O'Brien, Susan, Lerner, Susan, Coombes, Kevin R., Schlette, Ellen, Ferrajoli, Alessandra, Barron, Lynn L., Kipps, Thomas J., Rassenti, Laura, Faderl, Stefan, Kantarjian, Hagop, Abruzzo, Lynne V.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916943/
https://ncbi.nlm.nih.gov/pubmed/19050308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184853
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