Relevance of the immunoglobulin V(H) somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens

Although immunoglobulin V(H) mutation status (IgV(H) MS) is prognostic in patients with chronic lymphocytic leukemia (CLL) who are treated with alkylating agents or single-agent fludarabine, its significance in the era of chemoimmunotherapy is not known. We determined the IgV(H) somatic mutation sta...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lin, Katherine I., Tam, Constantine S., Keating, Michael J., Wierda, William G., O'Brien, Susan, Lerner, Susan, Coombes, Kevin R., Schlette, Ellen, Ferrajoli, Alessandra, Barron, Lynn L., Kipps, Thomas J., Rassenti, Laura, Faderl, Stefan, Kantarjian, Hagop, Abruzzo, Lynne V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916943/
https://ncbi.nlm.nih.gov/pubmed/19050308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184853
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