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SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value

SF3B1 mutations were recently reported in myelodysplastic syndromes (MDSs), especially in the presence of ring sideroblasts (RSs). We sought to define the interaction between SF3B1 mutations, morphology, karyotype, and prognosis in MDS with more than or equal to 15% RS (MDS-RS). We studied 107 patie...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Patnaik, Mrinal M., Lasho, Terra L., Hodnefield, Janice M., Knudson, Ryan A., Ketterling, Rhett P., Garcia-Manero, Guillermo, Steensma, David P., Pardanani, Animesh, Hanson, Curtis A., Tefferi, Ayalew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916563/
https://ncbi.nlm.nih.gov/pubmed/22096241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377994
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