MK2 inhibitor reduces alkali burn-induced inflammation in rat cornea

MK2 activation by p38 MAPK selectively induces inflammation in various diseases. We determined if a MK2 inhibitor (MK2i), improves cornea wound healing by inhibiting inflammation caused by burning rat corneas with alkali. Our study, for the first time, demonstrated that MK2i inhibited alkali burn-in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Chen, Yanfeng, Yang, Wenzhao, Zhang, Xiaobo, Yang, Shu, Peng, Gao, Wu, Ting, Zhou, Yueping, Huang, Caihong, Reinach, Peter S., Li, Wei, Liu, Zuguo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916419/
https://ncbi.nlm.nih.gov/pubmed/27329698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28145
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