Proteins on exocytic vesicles mediate calcium-triggered fusion.
In many exocytic systems, micromolar concentrations of intracellular Ca2+ trigger fusion. We find that aggregates of secretory granules isolated from sea urchin eggs fuse together when perfused with greater than or equal to 10 microM free Ca2+. Mixing of membrane components was demonstrated by trans...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1992
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1584814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4749 |
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